The young reporter Ángela is rescued from the building and taken to an oil tanker to be examined. However, it is unbeknown to the soldiers that she carries the seed of the mysterious demonic virus. – IMDb

From the looks of this trailer this film will completely ignore the third movie which was set at a wedding (and I don’t think that is a bad thing because I had mixed feelings about that film) but I also recall that Angela was possessed by a demon not just infected with the zombie demon virus. Yet she seems pretty normal in this trailer.
I do like that claustrophobic and hopeless feeling that being set on a ship in the middle of the sea provides. I am pretty stoked to see what this installment of the franchise will be like.